A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez

Study Identifier:
CLI-FILSVAA1-01
ClinicalTrials.gov Identifier:
NCT06423573
EudraCT Identifier:
N/A
EU CT ID:
N/A
Study Contact Information:
+3905212791 or [email protected]
Recruiting

Study Details

Medical Condition
  • Epidermolysis Bullosa
Study Drug
  • Drug: Filsuvez
Date
Dec 2024 - Nov 2031
Phase 1
Phase 2
Phase 3
Phase 4
N/A
Patient Requirements
Sex: Female & Male
Age: N/A
Requirements Information
Inclusion and Exclusion Criteria
Inclusion Criteria
  • Patients with a confirmed diagnosis of dystrophic EB or junctional EB
Exclusion Criteria
  • None
Healthy Volunteers
No

Protocol Summary

In patients with epidermolysis bullosa (EB), collagen does not form properly, so their skin is very fragile and blisters easily. Such patients are also at greatly increased risk of developing skin cancers. Filsuvez is a topical gel used to promote healing of skin lesions in patients with certain types of EB. In this observational study, patients with either dystrophic EB (DEB) or junctional EB (JEB) will receive standard of care treatment, whether Filsuvez or something else, and will be followed for a minimum of 3 years. The main purpose is to see if the use of Filsuvez affects the likelihood of developing skin malignancies in these patient populations.

Study Locations

Location
Status
Location
Lucile Packard Children's Hospital
Palo Alto, California, United States, 94304
Contact: Joyce Teng, MD
Phone: 650-724-9627
Status
Not yet recruiting
Location
UCHealth / Children's Hospital Colorado
Aurora, Colorado, United States, 80045
Contact: Emily Gorell, DO
Phone: 707-319-9269
Status
Not yet recruiting
Location
UF College of Medicine
Gainesville, Florida, United States, 32606
Contact: Michael Lavery, MD
Phone: 352-594-1547
Status
Not yet recruiting
Location
Cincinnati Children's
Cincinnati, Ohio, United States, 45229
Contact: Kalyani Marathe
Phone: 513-636-2009
Status
Not yet recruiting
Location
Childrens Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104
Contact: Marissa Perman-Laskin, MD
Phone: 215-590-1930
Status
Not yet recruiting
Location
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Contact: Lara Wine Lee, MD
Phone: 843-792-3021
Status
Not yet recruiting
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